{"id":17990,"date":"2025-06-12T06:55:29","date_gmt":"2025-06-11T23:55:29","guid":{"rendered":"https:\/\/www.tibdglobal.com\/product\/nahlsgen\/"},"modified":"2026-10-06T13:31:20","modified_gmt":"2026-10-06T06:31:20","slug":"nahlsgen","status":"publish","type":"product","link":"https:\/\/www.tibdglobal.com\/en\/product\/nahlsgen\/","title":{"rendered":"NAHLSGEN SKIN CELL REPAIR &#038; BARRIER STRENGTHENING EXTRACT"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_section][vc_row][vc_column]\n\t\t<div id=\"wd-691da7b361558\" class=\"title-wrapper wd-wpb wd-set-mb reset-last-child  wd-rs-691da7b361558 wd-title-color-white wd-title-style-simple text-center  wd-underline-colored\">\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title  wd-font-weight-500 wd-fontsize-l\" ><span class=\"ez-toc-section\" id=\"nahlsgen\"><\/span>Nahlsgen<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"title-after_title reset-last-child  wd-fontsize-xs\">An active ingredient innovation for skin cell repair and a stronger skin barrier<\/div>\n\t\t\t\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t[\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=&#8221;&#8221; woodmart_inline=&#8221;no&#8221; text_larger=&#8221;no&#8221;]\r\n<h4><span class=\"ez-toc-section\" id=\"nahlsgen_cellular_skin_renewal_science_from_japan\"><\/span><strong>Nahlsgen: Cellular Skin Renewal Science from Japan<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\r\n<strong>Nahlsgen<\/strong> is a synthetic active ingredient developed at <strong>Deep Tech Synthetic Innovation<\/strong> level, designed from in-depth biochemical and molecular research to mimic the skin&#8217;s natural repair mechanisms, with the aim of <strong>stimulating skin cell repair (<\/strong><strong>Skin Cell Repair)<\/strong> and <strong>strengthening the skin barrier (<\/strong><strong>Barrier Strengthening)<\/strong> so they work fully and at their best.[\/vc_column_text][vc_column_text css=&#8221;&#8221; woodmart_inline=&#8221;no&#8221; text_larger=&#8221;no&#8221;]It integrates knowledge of biochemistry and protein structure to precisely activate the skin repair mechanism that already exists in the human body. Nahlsgen stands out for its ability to <strong>increase collagen and elastin production,<\/strong>, <strong>restore the skin barrier (<\/strong><strong>Skin Barrier)<\/strong>, and <strong>help prevent premature signs of ageing<\/strong> in a systematic way.\r\n\r\n<strong>The pain point of ordinary extracts<\/strong> is instability and an inability to truly penetrate skin cells. Nahlsgen is designed as a synthetic active with a small molecular size of just <strong>331.26 daltons,<\/strong> so it can penetrate deep into the skin and reach its target, delivering higher performance than ordinary extracts at the same level.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=&#8221;&#8221; woodmart_inline=&#8221;no&#8221; text_larger=&#8221;no&#8221;]\r\n<h4><span class=\"ez-toc-section\" id=\"a_scientific_collaboration_that_changes_the_future_of_skincare\"><\/span><strong>A Scientific Collaboration That Changes the Future of Skincare<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\r\nNahlsgen was discovered through a collaboration between <strong>Graduate School of Human Life Science, Osaka City University<\/strong> and <strong>Chemical Laboratory, Graduate School of Engineering, Kyoto University<\/strong>\r\n\r\nin <strong>AD <\/strong><strong>2012<\/strong> The scientists discovered a new synthetic molecule that effectively activates the skin&#8217;s intrinsic regeneration power at the cellular level. This was the starting point of an innovation that was later patented and used in premium products worldwide.[\/vc_column_text][vc_column_text css=&#8221;&#8221; woodmart_inline=&#8221;no&#8221; text_larger=&#8221;no&#8221;]The discovery aimed to address a key problem of age-related skin cell decline. Researchers found that, with age, fibroblasts produce less of key proteins such as <strong>collagen (<\/strong><strong>Collagen)<\/strong>, <strong>elastin (<\/strong><strong>Elastin)<\/strong> and <strong>HSP47<\/strong> , a protein that controls collagen quality. The result is skin that loses elasticity, develops wrinkles and has a weaker barrier. Nahlsgen was developed as a synthetic molecule that can \u201creactivate skin cells to work like younger skin\u201d without causing irritation or side effects.[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section woodmart_stretch_content=&#8221;section-stretch&#8221; woodmart_bg_position=&#8221;center-top&#8221; css=&#8221;.vc_custom_1763551393473{background-image: url(https:\/\/www.tibdglobal.com\/wp-content\/uploads\/2025\/10\/gradient-dark-blue-mobile-wallpaper-scaled.jpg?id=17487) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221; woodmart_css_id=&#8221;691da8841a988&#8243; responsive_spacing=&#8221;eyJwYXJhbV90eXBlIjoid29vZG1hcnRfcmVzcG9uc2l2ZV9zcGFjaW5nIiwic2VsZWN0b3JfaWQiOiI2OTFkYTg4NDFhOTg4Iiwic2hvcnRjb2RlIjoidmNfc2VjdGlvbiIsImRhdGEiOnsidGFibGV0Ijp7fSwibW9iaWxlIjp7fX19&#8243; mobile_bg_img_hidden=&#8221;no&#8221; tablet_bg_img_hidden=&#8221;no&#8221; woodmart_parallax=&#8221;0&#8243; woodmart_gradient_switch=&#8221;no&#8221; woodmart_box_shadow=&#8221;no&#8221; wd_z_index=&#8221;no&#8221; woodmart_disable_overflow=&#8221;0&#8243;][vc_row][vc_column]\n\t\t<div id=\"wd-691da8ba410ed\" class=\"title-wrapper wd-wpb wd-set-mb reset-last-child  wd-rs-691da8ba410ed wd-title-color-white wd-title-style-bordered text-center  wd-underline-colored\">\n\t\t\t\n\t\t\t<div class=\"liner-continer\">\n\t\t\t\t<h4 class=\"woodmart-title-container title  wd-font-weight-500 wd-fontsize-l\" ><span class=\"ez-toc-section\" id=\"nahlsgen_certified_mark\"><\/span>Nahlsgen Certified Mark<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;17549&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; css=&#8221;&#8221; parallax_scroll=&#8221;no&#8221; woodmart_inline=&#8221;no&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;17525&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; css=&#8221;&#8221; parallax_scroll=&#8221;no&#8221; woodmart_inline=&#8221;no&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;17511&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; css=&#8221;&#8221; parallax_scroll=&#8221;no&#8221; woodmart_inline=&#8221;no&#8221;][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row][vc_column][vc_column_text css=&#8221;&#8221; woodmart_inline=&#8221;no&#8221; text_larger=&#8221;no&#8221;]\r\n<h4><span class=\"ez-toc-section\" id=\"mechanism_of_action_and_properties\"><\/span><strong>Mechanism of Action and Properties<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\r\nNahlsgen helps renew the skin at several levels of the skin structure through biological mechanisms confirmed by research:\r\n<ol>\r\n \t<li><strong>Stimulates fibroblast activity<\/strong>\r\nIncreases production of collagen, elastin and structural skin proteins<\/li>\r\n \t<li><strong>Strengthens the skin barrier<\/strong>\r\nHelps skin retain moisture, reduces water loss (TEWL) and helps prevent irritation<\/li>\r\n \t<li><strong>Protects skin from radiation damage <\/strong><strong>UV<\/strong>\r\nIncreases glutathione levels in skin cells, which play a role in antioxidant defence<\/li>\r\n \t<li><strong>Works synergistically with vitamin C (<\/strong><strong>Vitamin C synergy)<\/strong>\r\nUsing them together supports collagen production more than using either alone<\/li>\r\n \t<li><strong>Anti-ROS <\/strong>Increases glutathione to defend against free radicals and UV damage<\/li>\r\n \t<li>Cell Repair &#038; Renewal: supports new cell formation and renews skin from within<\/li>\r\n \t<li>Skin Barrier Strengthening: reinforces the skin barrier, reduces water loss (TEWL) and improves resilience to pollution<\/li>\r\n \t<li>Anti-Inflammatory: calms mild skin inflammation, soothes and reduces redness<\/li>\r\n \t<li>Moisture Retention: long-lasting hydration for plumper, smoother-looking skin<\/li>\r\n<\/ol>\r\n[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section]<\/div>","protected":false},"excerpt":{"rendered":"excerpt","protected":false},"featured_media":18176,"template":"","meta":{"episode_type":"","audio_file":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","filesize_raw":""},"product_brand":[],"product_cat":[231],"product_tag":[],"class_list":{"0":"post-17990","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-active-ingredients-en","8":"first","9":"instock","10":"shipping-taxable","11":"product-type-simple"},"tibi_services_grid_image":"","_links":{"self":[{"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/product\/17990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/media\/18176"}],"wp:attachment":[{"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/media?parent=17990"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/product_brand?post=17990"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/product_cat?post=17990"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.tibdglobal.com\/en\/wp-json\/wp\/v2\/product_tag?post=17990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}