LIPOBROME

Lipobrome: pineapple core extract that supports protein digestion and joint comfort

From Pineapple Core to an Innovative Enzyme for Health

Pineapple (Ananas comosus) is not only an important economic crop but also a source of bromelain, a protease enzyme with high, widely recognised biological potential. Its ability to break down proteins and its anti-inflammatory properties have drawn interest in medicine, nutrition and beauty, from supporting digestion to exfoliating and soothing irritated skin.

However, although many studies confirm the benefits of bromelain, commercial use faces a major challenge: enzyme instability. Bromelain’s three-dimensional structure, which is key to its activity, is highly sensitive to temperature, light, pH and moisture, leading to denaturation and rapid loss of enzymatic activity in product formulas.

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Lipobrome

From Agricultural By-product to High-Value Active Ingredient

To overcome these limits and unlock the full potential of pineapple enzymes, TIBD researched and developed “Lipobrome”, an active ingredient innovation that combines natural value with advanced biotechnology, built on two key principles:

Pineapple rhizomes, the raw material of LIPOBROME

Sustainable use of raw materials (Upcycling Pineapple Core): Although bromelain can be extracted from every part of the pineapple, including the stem, leaves and fruit, TIBD innovates with sustainability as a priority. We developed Lipobrome from the pineapple core specifically, an agricultural by-product that is often overlooked or discarded. This Upcycling approach not only supports zero waste but also turns an overlooked raw material into a high-performance active ingredient, fully in line with circular economy principles.

2. Nano-encapsulation technology (Nano-Encapsulation Stabilization): TIBD encapsulates the extracted bromelain in nano-scale liposomes. This creates a molecular shield that protects the enzyme’s structure from external factors, making Lipobrome many times more stable than conventional enzyme forms and allowing controlled release at the target site.

How Lipobrome

Lipobrome is designed to support health and beauty through four key biological mechanisms:

Enhanced proteolytic activity Supports protein digestion in the digestive system and helps reduce bloating after high-protein meals.
Anti-inflammatory and anti-edematous activity Helps modulate inflammatory processes, supporting faster recovery of muscles and joints.
Skin barrier recovery Strengthens the skin, reduces transepidermal water loss (TEWL) and helps skin retain moisture for longer.
Mild exfoliation Bromelain helps break down keratin proteins in dead outer skin cells, leaving skin smoother and brighter-looking without irritation.